DPPA5 Polyklonale Antilichaam, Cy5,5 Vervoeging

DPPA5 is a 116 amino acid protein that localizes to the cytoplasm and contains one KH domain. Expressed in embryonic germ (EG), primordial germ (PG) and embryonic stem (ES) cells, DPPA5 plays an important role in the maintenance of ES cell pluripotency and may be necessary for proper embryogenesis. The gene encoding DPPA5 maps to human chromosome 6, which contains 170 million base pairs and comprises nearly 6% of the human genome. Deletion of a portion of the q arm of chromosome 6 is associated with early onset intestinal cancer, suggesting the presence of a cancer susceptibility locus. Additionally, Porphyria cutanea tarda, Parkinson's disease, Stickler syndrome and a susceptibility to bipolar disorder are all associated with genes that map to chromosome 6.

Developmental pluripotency associated 5; DPPA5; Embryonal stem cell specic gene 1 protein; Esg 1; ESG1; hDPPA5; DPPA5_HUMAN.

340168

Cytoplasm

1-100/116

DPPA5

Cy5.5

KLH conjugated synthetic peptide derived from human DPPA5

IF (IHC-P), IF (IHC-F), IF (ICC)

Purified by Protein A.

675nm/694nm

1µg/µl

IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Unmodified

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

340168

Human, Mouse, Rat, Rabbit