DPYD-antilichaam

The protein encoded by this gene is a pyrimidine catabolic enzyme and the initial and rate-limiting factor in the pathway of uracil and thymidine catabolism. Mutations in this gene result in dihydropyrimidine dehydrogenase deficiency, an error in pyrimidine metabolism associated with thymine-uraciluria and an increased risk of toxicity in cancer patients receiving 5-fluorouracil chemotherapy. Two transcript variants encoding different isoforms have been found for this gene.

1806

Q12882

Human, Mouse

Recombinant fusion protein containing a sequence corresponding to amino acids 1-173 of human DPYD (NP_001153773.1) .

Unconjugated

Primary Antibodies

Signal Transduction

Affinity purification

THP-1

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

Observed: 112kDa

IgG

WB: 1:500 - 1:2000

DPYD

Mouse liver

Dihydropyrimidine dehydrogenase

Homo sapiens

DHP, DHPDHASE, DPD, dihydropyrimidine dehydrogenase [NADP (+) ], dihydrothymine dehydrogenase, dihydrouracil dehydrogenase

WB

Liquid