DR3 (Wsl-1, Apo-3, TRAMP, LARD1-5, Death Receptor3) (MaxLight 750)

[DR3]

Human

Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: MaxLight750 conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Recognizes a 59kD apoptosis related protein designated DR3 (death receptor-3).DR3 is a cell surface receptor with a death domain, with functional similarities to TNFR1 and Fas (CD95).The ligand for DR3 has very recently been identified and has been termed Apo-3L.DR3 itself has also been called Wsl-1, Apo-3, TRAMP and LARD and functionally induces apoptosis and NF-KB activation.

[DR3]