DR6 Proteïne, Muis, Recombinant (hFc & Zijn)
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
Tumor necrosis factor receptor superfamily member 21 (DR6) is a single-pass type I membrane protein and contains 1 death domain and 4 TNFR-Cys repeats. The protein may activate NF-kappa-B and promote apoptosis and it may activate JNK and be involved in T-cell differentiation.It is required for both normal cell body death and axonal pruning. Trophic-factor deprivation triggers the cleavage of surface APP by beta-secretase to release sAPP-beta which is further cleaved to release an N-terminal fragment of APP (N-APP) . N-APP binds TNFRSF21 triggering caspase activation and degeneration of both neuronal cell bodies (via caspase-3) and axons (via caspase-6) .
Ice Packs
-20°C
Beschrijving
DR6 Proteïne, Muis, Recombinant (hFc & Zijn) Beschikbaar in 5 µg. Bestel eenvoudig online met snelle levering.
Specificaties
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