DRAK1 Antilichaam

DRAK1 Antibody: Apoptosis is mediated by death domain containing adapter molecules and a caspase family of proteases. Certain serine/threonine protein kinases, such as ASK-1 and RIP, are mediators of apoptosis. Two novel serine/threonine kinases that induce apoptosis were recently identified and designated DRAK1 and DRAK2 for DAP kinase-related apoptosis-inducing protein kinases. DRAKs contain an N-terminal kinase domain and a C-terminal regulation domain. Overexpression of DRAK1 induces apoptosis. DRAKs have high sequence homology to DAP and ZIP kinases, and they represent a novel family of serine/threonine kinases, which mediates apoptosis through their catalytic activities. DRAK1 is located in nucleus and the messenger RNA was ubiquitously expressed in human tissues.

9263

Q9UEE5

Q9UEE5

Human

Unconjugated

Primary Antibodies

Apoptosis, Autophagy

DRAK1 Antibody is affinity chromatography purified via peptide column.

Cat. No. 1202 - A431 Cell Lysate

1 mg/ml

Predicted species reactivity based on immunogen sequence: Rabbit: (73%)

DRAK1 Antibody is supplied in PBS containing 0.02% sodium azide.

None

Blue Ice

DRAK1 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

50 kDa

IgG

No cross responses to DRAK2, DAP or ZIP kinases.

STK17A

Cat. No. 1206 - MOLT4 Cell Lysate

Cat. No. 17-006 - MOLT-4 Cell Slide

Serine/threonine kinase 17a

Homo sapiens

Sanjo H, Kawai T, Akira S. DRAKs, novel serine/threonine kinases related to death-associated protein kinase that trigger apoptosis. J Biol Chem 1998;273:29066-71

DRAK1 Antibody: DRAK1, DRAK1, DAP kinase-related apoptosis-inducing protein kinase 1

ELISA, WB, ICC, IF

14423930

Liquid