DRAK2 Antilichaam

DRAK2 Antibody: Apoptosis is mediated by death domain containing adapter molecules and a caspase family of proteases. Certain serine/threonine protein kinases, such as ASK-1 and RIP, are mediators of apoptosis. Two novel serine/threonine kinases that induce apoptosis were recently identified and designated DRAK1 and DRAK2 (for DAP kinase-related apoptosis-inducing protein kinases) . DRAKs contain an N-terminal kinase domain and a C-terminal regulation domain. Overexpression of DRAK2 induces apoptosis. DRAKs have high sequence homology to DAP and ZIP kinases, and they represent a novel family of serine/threonine kinases, which mediates apoptosis through their catalytic activities. DRAK2 is located in nucleus and the messenger RNA was ubiquitously expressed in human tissues.

9262

O94768

AB011421

Human

Unconjugated

Primary Antibodies

Apoptosis, Autophagy

DRAK2 Antibody is Ion exchange chromatography purified.

Cat. No. 1205 - Jurkat Cell Lysate

1 mg/ml

Predicted species reactivity based on immunogen sequence: Mouse: (93%), Rat: (93%)

DRAK2 Antibody is supplied in PBS containing 0.02% sodium azide.

None

Blue Ice

DRAK2 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

IgG

It has no cross responses to DAP or ZIP kinases. The approximately 70 kDa band is probably non-related to DRAK2 although it is peptide blockable.

STK17B

Cat. No. 17-005 - Jurkat Cell Slide

Serine/threonine kinase 17b

Homo sapiens

Sanjo H, Kawai T, Akira S. DRAKs, novel serine/threonine kinases related to death-associated protein kinase that trigger apoptosis. J Biol Chem 1998;273:29066-71 (RD1299)

DRAK2 Antibody: DRAK2, DRAK2, DAP kinase-related apoptosis-inducing protein kinase 2

ELISA, WB, ICC

3834355

Liquid