DRAMP18563

DRAMP18563 (MAP-04-02) is a linear antimicrobial peptide that can act as a delivery vector to transport dual-ring peptide inhibitors that cannot penetrate the outer membrane of Gram-negative bacteria to their target sites. DRAMP18563 can be used to study the delivery strategies of dual-ring peptide inhibitors[1].

2699627-67-1

MAP-04-02

12352209

Bacterial

Anti-infection

COVID-19-immunoregulation

Infection

O=C(N[C@@H](CO)C(N[C@@H](CC(C)C)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](C(C)C)C(N[C@@H](CC1=CNC2=CC=CC=C12)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CO)C(N[C@@H](CC3=CNC4=CC=CC=C34)C(N[C@@H](CCCNC(N)=N)C(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H](CCCCN)N

C69H112N26O14

1529.79

[1]Rowland CE, et al. Discovery and chemical optimisation of a potent, Bi-cyclic antimicrobial inhibitor of Escherichia coli PBP3. Commun Biol. 2025 May 28;8 (1) :819.

Room temperature

http://file.medchemexpress.com/batch_PDF/HY-P11225/

Peptides

No Development Reported