DRB
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
A classic inhibitor of transcription by RNA polymerase II. A relatively selective inhibitor of Cdk9 (IC50=3 μM), the kinase of the positive transcription elongation factor b (P-TEF-b) required for processive transcription elongation by RNA polymerase II.1,2 Also inhibits casein kinase II, IC50=4-10 μM. 3 Suppresses the SIRT1/CK2α pathway and enhances the radiosensitivity of human cancer cells.4 Kinase-independent activities of Cdk9 such as glucocorticoid receptor modulation are not inhibited by DRB.5
Unconjugated
White solid
-20°C
Beschrijving
DRB Beschikbaar in 10 mg. Bestel eenvoudig online met snelle levering.
Specificaties
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