DRD3 Antilichaam

This gene encodes the D3 subtype of the five (D1-D5) dopamine receptors. The activity of the D3 subtype receptor is mediated by G proteins which inhibit adenylyl cyclase. This receptor is localized to the limbic areas of the brain, which are associated with cognitive, emotional, and endocrine functions. Genetic variation in this gene may be associated with susceptibility to hereditary essential tremor 1. Alternative splicing of this gene results in transcript variants encoding different isoforms, although some variants may be subject to nonsense-mediated decay (NMD) .

1814

P35462

Human, Mouse, Rat

Recombinant fusion protein containing a sequence corresponding to amino acids 213-329 of human DRD3 (NP_000787.2) .

Unconjugated

Primary Antibodies

Neuroscience

Affinity purification

Mouse brain

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

Observed: 44kDa

IgG

DRD3

Dopamine receptor D3

Homo sapiens

DRD3, D3 dopamine receptor, D3DR, Dopamine 3 receptor, Dopamine receptor D3, D3nf, Essential tremor 1, ETM1, FET1, D (3) dopamine receptor, Dopamine D3 receptor

WB, IHC, IF

Liquid