DRD4 Antilichaam

This gene encodes the D4 subtype of the dopamine receptor. The D4 subtype is a G-protein coupled receptor which inhibits adenylyl cyclase. It is a target for drugs which treat schizophrenia and Parkinson disease. Mutations in this gene have been associated with various behavioral phenotypes, including autonomic nervous system dysfunction, attention deficit/hyperactivity disorder, and the personality trait of novelty seeking. This gene contains a polymorphic number (2-10 copies) of tandem 48 nt repeats; the sequence shown contains four repeats.

1815

P21917

Mouse, Rat

A synthetic peptide corresponding to a sequence within amino acids 100-200 of human DRD4 (NP_000788.2) .

Unconjugated

Primary Antibodies

Neuroscience

Affinity purification

Mouse brain

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

Observed: 52kDa

IgG

DRD4

Rat brain

Dopamine receptor D4

Homo sapiens

DRD4, dopamine receptor D4, D4DR, D (2C) dopamine receptor, dopamine D4 receptor, seven transmembrane helix receptor

WB, IHC

Liquid