DS02312223
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
DS02312223 (D223) is a molecular glue that promotes the binding of RAS to PI3Kα, thereby enhancing glucose uptake in the absence of insulin. DS02312223 is used in diabetes research[1].
2253733-45-6
D223
12352005
Molecular Glues
PROTAC
Metabolism-sugar/lipid metabolism
Metabolic Disease
CC(C)(OC(NCCOCCOC1=C(C=CC=C1)C2=C3SC=CC3=C(N=N2)NC4=C(C=C(C=C4)CC(N)=O)F)=O)C
C29H32FN5O5S
581.66
[1]Terayama K, et al. Molecular glues that facilitate RAS binding to PI3Kα promote glucose uptake without insulin. Science. 2025 Jul 24;389 (6758) :402-408.
Room temperature
http://file.medchemexpress.com/batch_PDF/HY-W1126235/
Reference compound1
No Development Reported
Beschrijving
DS02312223 (D223) is a molecular glue that promotes the binding of RAS to PI3Kα, thereby enhancing glucose uptake in the absence of insulin. DS02312223 is used
Specificaties
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