DSM1465
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
Dehydrogenase, Parasite
Microbiology/Virology, Metabolism
DSM1465 (Compound 82) is a potent and selective inhibitor of P. falciparum dihydroorotate dehydrogenase (PfDHODH) with an IC50 value of 15 nM. It inhibits P. falciparum 3D7 (Pf3D7) parasites with an EC50 value of 1.4 nM and demonstrates significant in vivo efficacy in humanized P. falciparum mouse models.
ClC1=C(C(F)(F)F)N=CC([C@](C2=C3C(C(N(C4CC4)C=N3)=O)=NN2C)(O)C(F)(F)F)=C1
C17H12ClF6N5O2
467.753
Ice Packs
-20°C
Beschrijving
DSM1465 Beschikbaar in 10 mg. Bestel eenvoudig online met snelle levering.
Specificaties
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