DTX2 Antilichaam - C-terminalgebied: FITC (ARP43285_P050-FITC)

Deltex homolog 2 (Drosophila)

RNF58

113878

Q6XM87

NP_001096066

Human, Mouse, Rat, Cow, Dog, Goat, Guinea Pig, Horse, Rabbit, Zebrafish

The immunogen is a synthetic peptide directed towards the C terminal region of human DTX2

DTX2 is a regulator of Notch signaling, a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations. DTX2 probably acts both as a positive and negative regulator of Notch, depending on the developmental and cell context and mediates the antineural activity of Notch, possibly by inhibiting the transcriptional activation mediated by MATCH1. It also functions as an ubiquitin ligase protein in vitro, suggesting that it may regulate the Notch pathway via some ubiquitin ligase activity.

KRTAP26-1; RFX6; KLC3; GLYCTK; DTX2; RIMBP3; C1orf94; NCALD; PLEKHF2; TRIM54; EIF4ENIF1; ALKBH4; UBE2D4; HPCAL4; SPG21; SEC22A; SPAG8; STX12; NCS1; FAM168A; RBPMS; SEC23B; ABHD16A; VSNL1; SUMO1; UBE2D3; UBE2D1; UBC; TRIP6; QARS; HDC; GOLGA2; FHL2; ARNT2

FITC: Fluorescein Isothiocyanate

Polyclonal Antibody

WB

Affinity Purified

0.5 mg/ml

Cow: 100%; Dog: 100%; Goat: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 93%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

62kDa

Wet Ice

575

DTX2

DTX2

Rabbit

Probable E3 ubiquitin-protein ligase DTX2

NM_001102596

EDCGTILIVYSIPHGIQGPEHPNPGKPFTARGFPRQCYLPDNAQGRKVLE