Duligotuzumab (Anti-EGFR & HER3)
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
1314238-96-4
MEHD7945A, RG 7597
C00873-1mg
EGFR
Protein Tyrosine Kinase
Duligotuzumab is a dual-action humanized IgG1 antibody that blocks ligand binding to the epidermal growth factor receptor (EGFR) and human epidermal growth factor receptor 3 (HER3) . By inhibiting these interactions, it disrupts signalling from all ligand-dependent HER dimers and induces antibody-dependent cell-mediated cytotoxicity. It exhibits enhanced efficacy in EGFR inhibitor-resistant SCCHN and NSCLC models, with potential benefits for tumors with high neuregulin 1 (NRG1) expression. MW: 144.78 KD.
-80°C (avoid freeze-thaw cycles)
Beschrijving
Duligotuzumab (Anti-EGFR & HER3) Beschikbaar in 1 mg. Bestel eenvoudig online met snelle levering.
Specificaties
Recent bekeken producten
PEPTIC DIGEST OF ANIMAL TISSUE (MEAT PEPTONE)
P16-102-01
500 g
GelRed® Agarose LE
#41029-5G
1x 5 g
HT115 (DE3) Super Competent Cells
D1045S
10x 100 μL
HT115
ACC-130
10 Tubes
Rat Reticulon-4 receptor, RTN4R ELISA Kit
MBS9325746-01
48 Well
Starfish Genomic DNA
GSF-390
0.025 mg
NPM2
570475-01
50 µg
15-PGDH Inhibitor Screening Kit (Fluorometric)
K503-100
100 Assays
Recent gezochte producten
MS Solution sufficient for 400 Mini, 142 Midi, 33 Maxi
MS10
Each
MS pipette, variable vol µme 10~100 µL
MSP-100
1 Unit
MS 12-ch pipette, variable vol µme 20~200 µL
MSP-12X200
1 Unit
MS 12-ch pipette, variable vol µme 2~20 µL
MSP-12X20
1 Unit
MS Rocking anti-moistured shaker with 30 x 30 cm platform and flat non-slip rubber mat
MS-NRK-3001
1 Unit
MS Orbital Shaker with 30 x 30 cm platform and flat non-slip rubber mat
MS-NOR-30
1 Unit
MS Reciprocal anti-moistured shaker with 30 x 30 cm platform and flat non-slip rubber mat
MS-NRC-3001
1 Unit
MS pipette, variable vol µme 1000~10000 µL
MSP-10000
1 Unit