DUSP6 Antilichaam

The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This protein product inactivates ERK2, is expressed in a variety of tissues with the highest levels in heart and pancreas, and unlike most other members of this family, is localized in the cytoplasm.

1848

Q16828

NP_001937.1

Human, Mouse, Rat

135-280

Unconjugated

Primary Antibodies

Signal Transduction

Immunoaffinity Purified

1 mg/mL

Phosphate-Buffered Saline. No preservatives added.

None

Blue Ice

DUSP6 antibody can be stored at 4˚ C for short term (weeks) . Long term storage should be at -20˚ C. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

15.1 kDa (calculated)

Dual specificity phosphatase 6 antibody can be used for the detection of Dual specificity phosphatase 6 by Western Blot.

DUSP6

Dual specificity phosphatase 6

Homo sapiens

MKP3, PYST1, Dual specificity protein phosphatase 6, Dual specificity protein phosphatase PYST1, MAP kinase phosphatase 3, HH19, MKP3, Dual specificity phosphatase 6

WB

4503419

Liquid