DUX4 Antilichaam - N-terminaal gebied: Biotine (ARP36096_P050-Biotine)

Double homeobox 4

DUX4L

100288687

Q9UBX2

NP_001280727.1

Human

The immunogen is a synthetic peptide directed towards the N-terminal region of human DUX4

This gene is located within a D4Z4 repeat array in the subtelomeric region of chromosome 4q. The D4Z4 repeat is polymorphic in length; a similar D4Z4 repeat array has been identified on chromosome 10. Each D4Z4 repeat unit has an open reading frame (named DUX4) that encodes two homeoboxes; the repeat-array and ORF is conserved in other mammals. The encoded protein has been reported to function as a transcriptional activator of paired-like homeodomain transcription factor 1 (PITX1; GeneID 5307) . Contraction of the macrosatellite repeat causes autosomal dominant facioscapulohumeral muscular dystrophy (FSHD) . Alternative splicing results in multiple transcript variants.

Biotin

Polyclonal Antibody

WB

Affinity Purified

0.5 mg/ml

Human: 100%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

93kDa

Wet Ice

853

DUX4

DUX4

Rabbit

Double homeobox protein 4

NM_001293798.1

TRGAEGTLGGRQGGREAGRNGGRDRATQGLGAGPREPGTDGGRKAGRKSG