DVL1 Antilichaam - middengebied: HRP (ARP32100_T100-HRP)

Dishevelled, dsh homolog 1 (Drosophila)

DVL, DRS2, DVL1L1, DVL1P1

1855

A6NKG8

EAW56226

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

The immunogen is a synthetic peptide directed towards the middle region of human DVL1

DVL1 is a cytoplasmic phosphoprotein that regulates cell proliferation, acting as a transducer molecule for developmental processes, including segmentation and neuroblast specification. DVL1 gene is a candidate for neuroblastomatous transformation. The Schwartz-Jampel syndrome and Charcot-Marie-Tooth disease type 2A have been mapped to the same region as DVL1 gene. The phenotypes of these diseases may be consistent with defects which might be expected from aberrant expression of a DVL gene during development.

NCK2; TRIM69; NUMA1; HUWE1; UBC; DVL2; WWOX; SIPA1; PSMA3; LRRK2; ITCH; HECW1; NEDD4; ANXA7; SDC4; NKD2; CYLD; SIRT1; CCDC88C; VANGL1; CXXC4; PPM1A; DYNLT1; HDHD2; BRD7; DAAM1; AXIN1; USP13; SMAD3; SMAD7; FRAT1; RAC1; DVL3; SMAD2; DVL1; SMAD4; CSNK1D; CSN

HRP: Horseradish Peroxidase

Polyclonal Antibody

WB

DVL1 is supported by BioGPS gene expression data to be expressed in HepG2

0.5 mg/ml

Cow: 93%; Dog: 93%; Guinea Pig: 93%; Horse: 93%; Human: 100%; Mouse: 93%; Rabbit: 93%; Rat: 93%; Zebrafish: 87%

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

38kDa

Wet Ice

353

DVL1

DVL1

Rabbit

NM_004421

LKITIANAVIGADVVDWLYTHVEGFKERREARKYASSLLKHGFLRHTVNK