DVL2 Antilichaam - N-terminaal gebied: Biotine (ARP32102_P050-Biotine)

Dishevelled, dsh homolog 2 (Drosophila)

1856

O14641

NP_004413

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Yeast, Zebrafish

The immunogen is a synthetic peptide directed towards the N terminal region of human DVL2

DVL2 is a member of the dishevelled (dsh) protein family. It is a 90-kD protein that undergoes posttranslational phosphorylation to form a 95-kD cytoplasmic protein, which may play a role in the signal transduction pathway mediated by multiple Wnt proteins. The mechanisms of dishevelled function in Wnt signaling are likely to be conserved among metazoans. This gene encodes a member of the dishevelled (dsh) protein family. The vertebrate dsh proteins have approximately 40% amino acid sequence similarity with Drosophila dsh. This gene encodes a 90-kD protein that undergoes posttranslational phosphorylation to form a 95-kD cytoplasmic protein, which may play a role in the signal transduction pathway mediated by multiple Wnt proteins. The mechanisms of dishevelled function in Wnt signaling are likely to be conserved among metazoans. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

UBC; NUMA1; IQGAP1; DVL3; DVL1; RNF185; WWOX; SQSTM1; IRS2; IRS1; TARS; GABARAPL1; CSNK1E; OTULIN; TP53; LYN; Smurf2; PLA2G12A; CTBP2; LRRK2; ATN1; RBFOX1; ITCH; ELAVL1; NHLRC1; MAP1LC3A; GABARAP; VHL; SIRT1; VANGL1; TCEB3B; CPSF7; SNF8; PPM1A; POLI; DYNL

Biotin

Polyclonal Antibody

IHC, WB

Affinity Purified

0.5 mg/ml

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Yeast: 82%; Zebrafish: 93%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

79kDa

Lee, Y.N., (2008) Cell. Signal. 20 (2), 443-452

Wet Ice

736

DVL2

DVL2

Rabbit

Segment polarity protein dishevelled homolog DVL-2

NM_004422

AGSSTGGGGVGETKVIYHLDEEETPYLVKIPVPAERITLGDFKSVLQRPA