Dy geeft toe-1 Antilichaam [3G4B6]

Dynamin-1 (Dyn1), with 864-amino acid protein (about 95 kDa), belongs to the dynamin family. Dynamin-1 (neuron-specific), dynamin-2 (ubiquitously expressed), and dynamin-3 (expressed only in the testis, brain, and lung), constitute the dynamin family. Members of the dynamin family are GPTase, microtubule-associated proteins which are involved in endocytosis, synaptic transmission and neurogenesis. Dynamin-1 is phosphorylated in nerve terminals exclusively in the cytosolic compartment and in vitro by protein kinase C. Dynamin-1 is a large GTPase enzyme required in membrane constriction and fission during multiple forms of endocytosis. Dynamin-1 is also a key molecule required for the recycling of synaptic vesicles in neurons, and it has been known that dynamin-1 gene expression is induced during neuronal differentiation.

1759

Q05193

Q05193

Human

Ni-NTA purified truncated recombinant Dynamin-1 expressed in E. Coli strain BL21 (DE3) .

3G4B6

Unconjugated

Primary Antibodies

Neuroscience

Batch dependent

Ascitic fluid containing 0.03% sodium azide.

None

Blue Ice

Dynamin-1 monoclonal antibody can be stored at -20˚ C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

IgG2a

DNM1

Dynamin 1

Homo sapiens

Annie Quan and Phillip J. Robinson. Methods Enzymol. 2005; 404:556-69.

Jiyun Yoo, Moon-Jin Jeong, Byoung-Mog Kwon. J. Biol. Chem., Mar 2002; 277: 11904 – 11909.

DNMDNM

ELISA, WB, IHC

172046078