Dynarrestine
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
Dynarrestin is a reversible inhibitor of cytoplasmic dyneins 1 and 2.1 It inhibits dynein 1-dependent microtubule binding and motility without affecting ATP hydrolysis as well as dynein 2-dependent intraflagellar transport of the cargo IFT88 and flux of Smoothened within cilia without interfering with ciliogenesis. Dynarrestin suppresses hedgehog-dependent proliferation of neuronal precursors and tumor cells. It binds protein tyrosine phosphatase interacting protein 51 (PTPIP51) leading to increased MAPK activation and complete blockade of Akt signaling in Her2 positive breast cancer cells (SKBR3) .2
Unconjugated
Pale pink/purple solid
-20°C
Beschrijving
Dynarrestine Beschikbaar in 5 mg. Bestel eenvoudig online met snelle levering.
Specificaties
Recent bekeken producten
CYP707A2 Antibody
GTR17947107
2 mg
SsDNA Assay Kit
12645ES60
100 Tests
Eco Alu MTP (HxD) 6x7=42 plates 35mm, 223x630x135mm
TE15336
1 Piece
Arachis hypogaea Lectin (PNA) - Biotinylated
21510020-1
5mg
Cellubrevin Antibody
MBS9436639-01
0.05 mL
Oxidative Stress Combo Assay Tissue Kit
EA-7008
1 Each
1,4- Dioxane Pure
1041330 500
500 mL
Benzonase ELISA Kit
EG23601S
96 Tests
Recent gezochte producten
Recombinant Deinococcus radiodurans Protein RecA (recA)
MBS1071366-01
0.05 mg (E-Coli)
Recombinant Deinococcus radiodurans Protein ApaG (apaG)
MBS1302345-01
0.05 mg (E-Coli)
Recombinant Deinococcus radiodurans Protein grpE (grpE)
MBS1306645-01
0.05 mg (E-Coli)
Recombinant Deinococcus radiodurans GTPase obg (obg)
MBS1312662-01
0.05 mg (E-Coli)
Recombinant Deinococcus radiodurans GTPase Era (era)
MBS1418228-01
0.05 mg (E-Coli)
Recombinant Deinococcus radiodurans GTPase Der (der)
MBS1445159-01
0.05 mg (E-Coli)
Recombinant Deinococcus radiodurans Enolase (eno)
MBS1455279-01
0.05 mg (E-Coli)
Recombinant Deinococcus radiodurans Protein nrdI (nrdI)
MBS1483359-01
0.05 mg (E-Coli)