DYRK3 Antilichaam - N-terminalgebied: HRP (ARP30648_P050-HRP)

Dual-specificity tyrosine- (Y) -phosphorylation regulated kinase 3

RED, REDK, DYRK5, hYAK3-2

8444

O43781

NP_003573

Human, Mouse

The immunogen is a synthetic peptide directed towards the N terminal region of human DYRK3

This gene product belongs to the DYRK family of dual-specificity protein kinases that catalyze autophosphorylation on serine/threonine and tyrosine residues. The members of this family share structural similarity, however, differ in their substrate specificity, suggesting their involvement in different cellular functions. The encoded protein has been shown to autophosphorylate on tyrosine residue and catalyze phosphorylation of histones H3 and H2B in vitro. Alternatively spliced transcript variants encoding different isoforms have been identified.

DYRK3; SORL1; FBXO25; PRNP; NEDD4L

HRP: Horseradish Peroxidase

Polyclonal Antibody

IF, WB

Affinity Purified

0.5 mg/ml

Human: 100%; Mouse: 86%

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

66kDa

Wet Ice

588

DYRK3

DYRK3

Rabbit

Dual specificity tyrosine-phosphorylation-regulated kinase 3

NM_003582

GDHTQHFLDGGEMKVEQLFQEFGNRKSNTIQSDGISDSEKCSPTVSQGKS