(E) -CLX-0921

(E) -CLX-0921 is the E-isomer of CLX-0921. CLX-0921 is an orally active PPARγ agonist with an IC50 of 1.54 μM. CLX-0921 has a potent antihyperglycemic activity, and can be used for the study of type 2 diabetes[1].

606932-81-4

12352005

PPAR

Cell Cycle/DNA Damage; Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor

Metabolic Disease

98.17

COC1=CC(OC)=CC(/C=C(C2=CC=C(C=C2)OC3=CC=C(C=C3)CC4SC(NC4=O)=O)/C(OC)=O)=C1

C28H25NO7S

519.57

[1]Debendranath Dey, et al. A novel peroxisome proliferator-activated gamma (PPAR gamma) agonist, CLX-0921, has potent antihyperglycemic activity with low adipogenic potential. Metabolism. 2003 Aug;52 (8) :1012-8.

Room Temperature

4°C (Powder, sealed storage, away from moisture)

http://file.medchemexpress.com/batch_PDF/HY-19394A/E-CLX-0921-SDS-MedChemExpress.pdf

Reference compound1

No Development Reported