(E) -JP-2-196 (TFA)
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
JP-2-196 (TFA) is a molecular glue handle that can bind to the E3-ubiquitin ligases (RNF126, LRSAM1, RNF40, MID2, and RNF14) in vitro. JP-2-196 (TFA) can be used to synthesize molecular glue degraders[1].
3065021-33-9
12352005
E3 Ligase Ligand-Linker Conjugates
PROTAC
Cancer
97.89
OC(C(F)(F)F)=O.O=C(N1CCNCC1)/C=C/C(C2=CC=C(C=C2)OC)=O
C17H19F3N2O5
388.34
[1]Toriki, E. S., et al., (2023) . Rational Chemical Design of Molecular Glue Degraders. ACS central science, 9 (5), 915–926.
Room Temperature
Store at room temperature, keep dry and cool
http://file.medchemexpress.com/batch_PDF/HY-W854844A/E-JP-2-196-TFA-SDS-MedChemExpress.pdf
Reference compound2
No Development Reported
Beschrijving
JP-2-196 (TFA) is a molecular glue handle that can bind to the E3-ubiquitin ligases (RNF126, LRSAM1, RNF40, MID2, and RNF14) in vitro. JP-2-196 (TFA) can be use
Specificaties
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