(E) -Tadehaginoside

(E) -Tadehaginoside is the E-isomer of Tadehaginoside. Tadehaginoside, a phenylpropanoid glycoside, is a regulator of lipogenesis and glucose consumption. Tadehaginoside has antioxygenic property. Tadehaginoside mediates liver protection against oxidative stress injury and inflammation by regulating Nrf2 and NF-κB signaling pathways in hepatocytes. Tadehaginoside can be used for the study of obesity and diabetes[1][2].

283176-41-0

12352005

Keap1-Nrf2; NF-κB

NF-κB

Metabolic Disease; Inflammation/Immunology

OC(C=C1)=CC=C1/C=C/C(OC[C@H]([C@H]([C@@H]([C@H]2O)O)O)O[C@H]2OC3=CC(O)=CC(O)=C3)=O

C21H22O10

434.39

[1]Tang A, et al. Antihepatotoxic effect of tadehaginoside, extracted from Tadehagi triquetrum (L.), against CCl4-lesioned rats through activating the Nrf2 signaling pathway and attenuating the inflammatory response. Inflammation. 2014 Aug;37 (4) :1006-14.|[2]Zhang X, et al. Tadehaginoside modulates lipogenesis and glucose consumption in HepG2 cells. Nat Prod Res. 2015;29 (24) :2287-90.

Room temperature

http://file.medchemexpress.com/batch_PDF/HY-N15691A/

Natural Products

No Development Reported