E2F2 Antilichaam

Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The DRTF1/E2F complex functions in the control of cell-cycle progression from g1 to s phase. E2F-2 binds specifically to RB1 protein, in a cell-cycle dependent manner.

1870

Q14209

NP_004082.1

Human, Mouse

E2F-2 antibody was raised against a peptide sequence around aa.425~429 (L-F-D-S-Y) derived from Human E2F-2.

Unconjugated

Primary Antibodies

Cell Cycle

Antibodies were purified by affinity-chromatography using epitope-specific peptide.

1 mg/mL

Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

None

Blue Ice

Store antibody at -20˚ C for up to one year.

45 kDa

This antibody detects endogenous level of total E2F-2 protein.

Western Blot: 1:500~1:1000

E2F2

E2F transcription factor 2

Homo sapiens

Rubin S. M., Gall A. -L., Zheng N., Pavletich N. P. Cell 123:1093-1106 (2005)

E2F-2, HER2, MLN19, NEU, NGL, E2F-2

WB

4758226

Liquid