E3 ligase ligand 51
Gecertificeerd

E3 ligase ligand 51

Catalog #: HY-W245311-01
Maat: 25 mg

Kwaliteit

ISO Gecertificeerd

Levering

24-48 uur

Prijs -1%
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Gratis verzending vanaf €100

Technische Specificaties

Description

E3 ligase Ligand 51 is the ligand for E3 ligase CRBN that can be used for synthesis of PROTAC BTK Degrader-12.

CAS Number

2703915-71-1

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Ligands for E3 Ligase

Related Pathways

PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer

Purity

98.0

Smiles

O=CC1CCN(C2=CC=C(N(C(N3)=O)CCC3=O)C=C2)CC1

Molecular Formula

C16H19N3O3

Molecular Weight

301.34

Precautions

H302, H315, H319, H335

References & Citations

[1]Wang H, et al., Degradation of bruton's tyrosine kinase (btk) by conjugation of btk inhibitors with e3 ligase ligand and methods of use. WO2021219070

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, protect from light, stored under nitrogen)

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-W245311/

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

Cereblon

Beschrijving

E3 ligase Ligand 51 is the ligand for E3 ligase CRBN that can be used for synthesis of PROTAC BTK Degrader-12.

Specificaties

ProductnaamE3 ligase ligand 51
Categorie
Beschikbare grootte25 mg
CatalogusnummerHY-W245311-01