E3 Ligase Ligand-linker Conjugate 157
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
E3 Ligase Ligand-linker Conjugate 157 is the conjugate composed of the E3 ligase ligand and the linker. E3 Ligase Ligand-linker Conjugate 157 can be used for synthesis of PROTAC degrader KT-253.
2502189-47-9
12352005
H302, H315, H319, H335
E3 Ligase Ligand-Linker Conjugates
PROTAC
Cancer-programmed cell death
Cancer
O=C(C(N1C2=CC=C(C3CCNCC3)C=C2N(C)C1=O)CC4)NC4=O
C18H22N4O3
342.39
H302, H315, H319, H335
[1]Chutake YK, et al., KT-253, A Novel MDM2 Degrader and p53 Stabilizer, Has Superior Potency and Efficacy Than MDM2 Small Molecule Inhibitors. Mol Cancer Ther. 2024 Dec 9.
Room Temperature
-20°C, 3 years; 4°C, 2 years (Powder)
http://file.medchemexpress.com/batch_PDF/HY-W1006706/
Reference compound1
No Development Reported
Beschrijving
E3 Ligase Ligand-linker Conjugate 157 is the conjugate composed of the E3 ligase ligand and the linker. E3 Ligase Ligand-linker Conjugate 157 can be used for sy
Specificaties
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