E3330
Gecertificeerd

E3330

Catalog #: bs-83746C-01
Maat: 5 mg

Kwaliteit

ISO Gecertificeerd

Levering

24-48 uur

Prijs -1%
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Gratis verzending vanaf €100
Technische Documentatie

Technische Specificaties

Background

E3330 is a hepatoprotective benzoquinone that inhibits TNF-α release via decreasing NFkB activation.1,2 It also is an inhibitor of AP endonuclease 1 (APE1) redox function.3 E3330 acts synergistically with cisplatin to increase cytotoxicity and impair cell migration and invasion in non-small cell lung cancer.4 Inhibition of APE1 with E3330 induces ferroptosis via impairment of AKT phosphorylation ultimately leading to Nrf2 degradation.5 It sensitizes osteosarcoma cells to ionizing radiation via ferroptosis induction.6

Conjugation

Unconjugated

Buffer

Orange solid

Storage Conditions

-20°C

Beschrijving

E3330 Beschikbaar in 5 mg. Bestel eenvoudig online met snelle levering.

Specificaties

ProductnaamE3330
Categorie
Beschikbare grootte5 mg
Catalogusnummerbs-83746C-01