ED11
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
1593480-56-8
Caspase
Apoptosis, Proteases/Proteasome
ED11 is a potent and selective caspase-6 inhibitor with an IC50 of 12.12 nM. It competes with Htt for the caspase-6 active site, thereby reducing Htt cleavage. ED11 is capable of crossing the blood-brain barrier (BBB) and holds potential for researching Huntington's disease (HD) .
C(=O)([C@H]1N(C([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CCCNC(=N)N)NC(CN)=O)=O)CCCCN)=O)CCCCN)=O)CCCNC(=N)N)=O)CCCNC(=N)N)=O)CCC(N)=O)=O)CCCNC(=N)N)=O)CCCNC(=N)N)=O)CCCNC(=N)N)=O)CCC1)N2[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(NCC(N[C@H](C(N[C@H](C(N[C@@H](CC(N)=O)C(O)=O)=O)CC(O)=O)=O)[C@@H](C)O)=O)=O)CC(O)=O)=O)CC(C)C)=O)C(C)C)=O)[C@H](CC)C)=O)CCC(O)=O)=O)CO)=O)CO)=O)CCC(N)=O)=O)CCC2
C116H205N47O37
2850.16
Ice Packs
-20°C
Beschrijving
ED11 Beschikbaar in 10 mg. Bestel eenvoudig online met snelle levering.
Specificaties
Recent bekeken producten
Biotin-Recombinant (sf9) Marburg virus glycoprotein (Musoke, HA-tag, >95%), purified
MVGP16-BTN
100 µL
MARV VP40/Marburg VP40 Protein (N-His, Lake Victoria marburgvirus (strain Musoke-80) (MARV) (Marburg virus (strain Kenya/Musoke/1980) ) )
P505862
100 µg
Hettich Centrifuge Rotanta 460R Refrigerated Large Volume
CEN0703
1 Each
X4RF Refrigerated Centrifuge
75009936
1 Each
Drug Stability Chamber
500-DSC102
1 Unit
Modular Incubator Chamber
MIC-101
1 Unit
CYP707A2 Antibody
GTR17947107
2 mg
SsDNA Assay Kit
12645ES60
100 Tests
Recent gezochte producten
Biotin-Recombinant (sf9) Marburg virus glycoprotein (Musoke, HA-tag, >95%), purified
MVGP16-BTN
100 µL
MARV VP40/Marburg VP40 Protein (N-His, Lake Victoria marburgvirus (strain Musoke-80) (MARV) (Marburg virus (strain Kenya/Musoke/1980) ) )
P505862
100 µg
X4RF Refrigerated Centrifuge
75009936
1 Each
Low Speed Refrigerated Centrifuge
LX104LSR
1 Unit
Low Speed Refrigerated Centrifuge
LX117LSR
1 Unit
Low Speed Refrigerated Centrifuge
LX124LSR
1 Unit
Blood Bank Refrigerator
LX4000BBR
1 Unit
Blood Bank Refrigerator
LX4002BBR
1 Unit