EfA4-agonistverbinding 23

EphA4 agonist compound 23 is a novel EphA4 agonist peptide mimic. EphA4 agonist compound 23 exhibits high affinity, high selectivity, and significant receptor activation ability. EphA4 agonist compound 23 is commonly used in the study of neurodegenerative diseases[1].

12352209

Ephrin Receptor

Protein Tyrosine Kinase/RTK

Neurological Disease

O=C(N1CCC[C@H]1C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CCCNC(N)=N)C(NC2=C(SC=C2C(N[C@@H](CCC(O)=O)C(N[C@@H](CC3=CNC4=C3C=CC=C4)C(N[C@@H](CO)C(N5CCC[C@H]5C(N)=O)=O)=O)=O)=O)C)=O)=O)CC6=CC=C(C7=CC=CC=C7)C=C6)=O)C(C)C)=O)CCCC)=O)CC8=CC=C(O)C=C8)=O)CCN

C79H103N17O16S

1578.83

[1]Prentiss AM, et al. Constrained β-Hairpins Targeting the EphA4 Ligand Binding Domain. J Med Chem. 2024 Dec 26;67 (24) :22245-22253.

Room temperature

http://file.medchemexpress.com/batch_PDF/HY-P11243/

Peptides

No Development Reported