EGFR-antilichaam - middengebied: Biotine (ARP61003 P050-Biotine)

Epidermal growth factor receptor

ERBB, ERRP, HER1, mENA, ERBB1, PIG61, NISBD2

1956

P00533

NP_958439

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer. Multiple alternatively spliced transcript variants that encode different protein isoforms have been found for this gene.

SEC61A1; UBC; CBL; ERBB4; EMD; SEC61B; DCBLD2; PML; DERL1; SOCS5; EPHA2; UBASH3B; PTPRF; EIF2AK2; MAP2K3; MAP2K2; PRKAG1; PRKAA1; PPP2R5C; PLK1; PLCG1; PFKP; PFKM; PFKL; PFKFB3; PDK1; VAV2; UCK2; UBE2G2; DNM2; CTNND1; CSNK2A1; CSNK1A1; CSK; AP3S1; AP2S1

Biotin

Polyclonal Antibody

WB

Affinity Purified

EGFR is strongly supported by BioGPS gene expression data to be expressed in MDA-MB231

0.5 mg/ml

Cow: 92%; Dog: 93%; Guinea Pig: 93%; Horse: 93%; Human: 100%; Mouse: 85%; Rabbit: 93%; Rat: 100%; Zebrafish: 75%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

69kDa

Wet Ice

628

EGFR

EGFR

Rabbit

Epidermal growth factor receptor

NM_201282

VTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLS