EIF4A1 Antibody - middle area: HRP (ARP48065 P050-HRP)

Eukaryotic translation initiation factor 4A1

DDX2A, EIF4A, EIF-4A, eIF4A-I, eIF-4A-I

1973

P60842

NP_001407

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Sheep, Yeast, Zebrafish

The immunogen is a synthetic peptide directed towards the middle region of human EIF4A1

EIF4A1 is an ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome. In the current model of translation initiation, eIF4A unwinds RNA secondary structures in the 5'-UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon.

HUWE1; UBC; FUS; SUMO2; SUMO3; STAU1; MDM2; SH3RF2; TRAP1; FBXO6; ADRB2; CD81; NPM1; VCAM1; ITGA4; FN1; ESR1; LIG4; RPLP0P6; TMEM43; NDUFB11; ZBTB43; GPRC5A; EIF4G3; EIF4H; VDAC3; UQCRFS1; SDHA; RPS26; RPL19; RPL8; RPSA; ILF2; HSP90AB1; HSPA5; EIF4G2; EIF

HRP: Horseradish Peroxidase

Polyclonal Antibody

WB

Affinity Purified

EIF4A1 is strongly supported by BioGPS gene expression data to be expressed in 721_B

0.5 mg/ml

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Sheep: 93%; Yeast: 92%; Zebrafish: 100%

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

46

Wet Ice

406

EIF4A1

EIF4A1

Rabbit

Eukaryotic initiation factor 4A-I

NM_001416

TMPSDVLEVTKKFMRDPIRILVKKEELTLEGIRQFYINVEREEWKLDTLC