EIF4E (Ab 209) Antilichaam

Recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation of protein synthesis and facilitates ribosome binding by inducing the unwinding of the mRNAs secondary structures.

1977

P06730

NP_001124150.1

Human, Mouse, Rat

EIF4E (Ab-209) antibody was raised against a peptide sequence around aa. 207~211 (S-G-S-T-T) derived from Human eIF4E.

Unconjugated

Primary Antibodies

Other

Antibodies were purified by affinity-chromatography using epitope-specific peptide.

1 mg/mL

Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

None

Blue Ice

Store antibody at -20˚ C for up to one year.

25 kDa

This antibody detects endogenous level of total elF4E protein.

Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100, Immunofluorescence: 1:100~1:200

EIF4E

Eukaryotic translation initiation factor 4E

Homo sapiens

Li BD, et al. (1998) Ann Surg; 227 (5) : 756-763Altmann M, et al. (1989) Nucleic Acids Res; 17 (18) : 7520De Gregorio E, et al. (2001) RNA; 7 (1) : 106-113Gu W, et al. (2004) Nucleic Acids Res; 32 (15) : 4448-4461Ohlmann T, et al. (1996) EMBO J; 15 (6) : 1371-1382

CBP, EIF4F, AUTS19, EIF4E1, EIF4EL1, A4, AD1, mRNA cap-binding protein, eIF-4F 25 kDa subunit

WB, IHC, IF

194578907

Liquid