EIF4EBP1 Antilichaam, KO Gevalideerd

This gene encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E), which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation.

1978

Q13541

Human, Mouse, Rat

A synthetic peptide corresponding to a sequence within amino acids 50 to the C-terminus of human EIF4EBP1 (NP_004086.1) .

Unconjugated

Primary Antibodies

Antibody is Knockout validated.

Obesity, Signal Transduction

Affinity purification

MCF7

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

Observed: 17kDa

IgG

EIF4EBP1

HeLa

SH-SY5Y

NIH/3T3

Mouse fat

Mouse heart

Eukaryotic translation initiation factor 4E binding protein 1

Homo sapiens

4E-BP1 Antibody: BP-1, 4EBP1, 4E-BP1, PHAS-I, Eukaryotic translation initiation factor 4E-binding protein 1, Phosphorylated heat- and acid-stable protein regulated by insulin 1

WB, IHC, IF

Liquid