Elab Bright Violet 421 Anti-Mouse CD49b Antibody[DX5]

DX5 antigen has been recently characterized as CD49b. It is a 150 kD integrin α chain also known as α2 integrin, VLA-2 α chain, and integrin α2 chain. CD49b non-covalently associates with CD29 (β1 integrin) to form the CD49b/CD29 complex known as VLA-2, a receptor for collagen and laminin. CD49b is expressed on platelets, the majority of NK cells, NKT cells, and a small subset of CD8+ T cells (this population can be significantly increased following viral infection) . DX5 is used for the identification and isolation of NK cells, and is especially useful for identifying NK cells in mice lacking the NK1.1 antigen.

CD49b

16398

Q62469

Mouse

CD49 antigen-like family member B; CD49b; Collagen receptor; GPIa; Integrin alpha-2; Platelet membrane glycoprotein Ia; VLA-2 subunit alpha; pan-NK cells

DX5

Elab Bright™Violet 421

FCM

Cell Adhesion; Cell Biology; Immunology; Innate Immunity

5 μL/Test

Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.

Ice bag

This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.

https://789.bio/eb/8zI95gFS

The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood) .

Rat IgM, κ