Elab Bright Violet 421 Anti-Mouse CD86 Antibody[GL1]

CD86 is an 80 kD immunoglobulin superfamily member also known as B7-2, B70, and Ly-58. CD86 is expressed on activated B and T cells, macrophages, dendritic cells, and astrocytes. CD86, along with CD80, is a ligand of CD28 and CD152 (CTLA-4) . CD86 is expressed earlier in the immune response than CD80. CD86 has also been shown to be involved in immunoglobulin class-switching and triggering of NK cell-mediated cytotoxicity. CD86 binds to CD28 to transduce co-stimulatory signals for T cell activation, proliferation, and cytokine production. CD86 can also bind to CD152, also known as CTLA-4, to deliver an inhibitory signal to T cells.

CD86

12524

P42082

Mouse

T-lymphocyte activation antigen CD86; Cd86; Activation B7-2 antigen; Early T-cell costimulatory molecule 1; ETC-1

GL1

Elab Bright™Violet 421

FCM

5 μL/Test

Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.

Ice bag

This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.

https://789.bio/eb/SimyVIIV

The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood) .

Rat IgG2a, κ