Elab Fluor® 488 Anti-Mouse CD8a Antibody[YTS169,4]

CD8, also known as Lyt-2, Ly-2, or T8, consists of disulfide-linked α and β chains that form the α (CD8a) /β (CD8b) heterodimer and α/α homodimer. CD8a is a 34 kD protein that belongs to the immunoglobulin family. The CD8 α/β heterodimer is expressed on the surface of most thymocytes and a subset of mature TCR α/β T cells. CD8 expression on mature T cells is non-overlapping with CD4. The CD8 α/α homodimer is expressed on a subset of γ/δ TCR-bearing T cells, NK cells, intestinal intraepithelial lymphocytes, and lymphoid dendritic cells. CD8 is an antigen co-receptor on T cells that interacts with MHC class I on antigen-presenting cells or epithelial cells. CD8 promotes T cell activation through its association with the TCR complex and protein tyrosine kinase lck.

CD8a

12525

P01731

Mouse

T8; Lyt2; Ly-2; T-cell surface glycoprotein Lyt-2; CD8a; CD8; AN00408

YTS169.4

Elab Fluor®488

FCM

0.5 mg/mL

Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.

Ice bag

This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.

https://789.bio/eb/lBivybPN

The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood) .

Rat IgG2b, λ