ELAC2 Antilichaam - C-terminaal gebied: Biotine (ARP41346 P050-Biotine)
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ELAC2 Antilichaam - C-terminaal gebied: Biotine (ARP41346 P050-Biotine)

Catalog #: ARP41346_P050-Biotin
Maat: 100 µL

Kwaliteit

ISO Gecertificeerd

Levering

24-48 uur

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Technische Documentatie

Technische Specificaties

Gene Name

ElaC homolog 2 (E. coli)

Gene Aliases

ELC2, HPC2, COXPD17

Gene ID

60528

Swiss Prot

Q9BQ52-2

Host

• Rabbit

Reactivity

Human, Mouse, Rat, Dog

Immunogen

The immunogen is a synthetic peptide directed towards the C-terminal region of Human ELAC2

Target

The protein encoded by this gene has a C-terminal domain with tRNA 3' processing endoribonuclease activity, which catalyzes the removal of the 3' trailer from precursor tRNAs. The protein also interacts with activated Smad family member 2 (Smad2) and its nuclear partner forkhead box H1 (also known as FAST-1), and reduced expression can suppress transforming growth factor-beta induced growth arrest. Mutations in this gene result in an increased risk of prostate cancer. Multiple transcript variants encoding different isoforms have been found for this gene.

Partner Proteins

UBC; SUMO2; SUMO1; NEDD8; XPO5; SNX5; ARIH1; TNPO3; WDR4; IPO7; TSN; SARS; PPP2CB; PFDN1; NRD1; HARS; FEN1; FOXH1; SMAD3; SMAD2; COPS5; ASCC2; NDUFA7; GOLM1; CUX1; PUF60

Clonality

• Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Sample Type

ELAC2 is supported by BioGPS gene expression data to be expressed in HepG2

Concentration

0.5 mg/ml

Homology

Dog: 100%; Human: 100%; Mouse: 83%; Rat: 83%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

55kDa

Shipping Conditions

Wet Ice

Protein Length

501

NCBI Gene Symbol

ELAC2

NCBI GB Accession Number

ELAC2

Host or Source

Rabbit

Protein Name

Zinc phosphodiesterase ELAC protein 2

Peptide Sequence

ITCNPEEFIVEALQLPNFQQSVQEYRRSAQDGPAPAEKRSQYPEIIFLGT

Beschrijving

ELAC2 Antilichaam - C-terminaal gebied: Biotine (ARP41346 P050-Biotine) Beschikbaar in 100 µL. Bestel eenvoudig online met snelle levering.

Specificaties

ProductnaamELAC2 Antilichaam - C-terminaal gebied: Biotine (ARP41346 P050-Biotine)
Categorie
Beschikbare grootte100 µL
CatalogusnummerARP41346_P050-Biotin