Elacridar (hydrochloride) (standaard)

Elacridar (hydrochloride) (Standard) is the analytical standard of Elacridar (hydrochloride) . This product is intended for research and analytical applications. Elacridar hydrochloride (GF120918A) is an orally active P-glycoprotein (P-gp) and breast cancer resistance protein (BCRP) inhibitor. Elacridar hydrochloride can be used to examine the influence of efflux transporters on agent distribution to brain and it can be used for the research of cancer[1][2].

143851-98-3

12352100

BCRP; P-glycoprotein; Reference Standards

Membrane Transporter/Ion Channel; Others

Cancer

O=C1C2=CC=CC(C(NC(C=C3)=CC=C3CCN4CC(C=C(C(OC)=C5)OC)=C5CC4)=O)=C2NC6=C1C=CC=C6OC.[H]Cl

C34H34ClN3O5

600.10

[1]Sane R, et al. Brain distribution and bioavailability of elacridar after different routes of administration in the mouse. Drug Metab Dispos. 2012 Aug;40 (8) :1612-9.|[2]Sato H, et al. Elacridar enhances the cytotoxic effects of sunitinib and prevents multidrug resistance in renal carcinoma cells. Eur J Pharmacol. 2015 Jan 5;746:258-66.

Room temperature

http://file.medchemexpress.com/batch_PDF/HY-50880R/

Reference Standards