ELOVL7 Antilichaam

ELOVL7 Antibody: Lipogenesis is a key event in the energy storage system and is controlled by the transcription factor sterol regulatory element-binding protein (SREBP) -1. Elongation of very long chain fatty acids protein 7 (ELOVL7) is a member of fatty acyl-CoA elongase gene family that elongates saturated very-long-chain fatty acids (SVLFA, C20:0-) and has been suggested to be involved in prostate cancer growth through saturated long-chain fatty acid metabolism. The metabolic pathways of long-chain fatty acids play an important role in the maintenance of membrane lipid composition and the generation of cell signaling precursor molecules such as eicosanoids and sphingosine-1 phosphate. Overexpression of ELOVL7 results in lipid accumulation in differentiated adipocytes; its expression is regulated by the microRNA miR-219.

79993

A1L3X0

NP_001098028

Human, Mouse

Unconjugated

Primary Antibodies

Homeostasis

ELOVL7 Antibody is affinity chromatography purified via peptide column.

Cat. No. 1304 - Human Liver Tissue Lysate

1 mg/mL

Predicted species reactivity based on immunogen sequence: Rat: (100%), Bovine: (100%)

ELOVL7 Antibody is supplied in PBS containing 0.02% sodium azide.

None

Blue Ice

ELOVL7 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

IgG

ELOVL7

Cat. No. 10-201 - Human Liver Tissue Slide

ELOVL family member 7, elongation of long chain fatty acids (yeast)

Homo sapiens

Tamura K, Makino A, Hullin-Matsuda F, et al. Novel lipogenic enzyme ELOVL7 is involved in prostate cancer growth through saturated long-chain fatty acid metabolism. Cancer Res.2009; 69:8133-40.

Leonard AE, Pereira SL, Sprecher H, et al. Elongation of long-chain fatty acids. Prog. Lipid Res.2004; 43:36-54.

Shin D, Shin JY, McManus MT, et al. Dicer ablation in oligodendrocytes provokes neuronal impairment in mice. Ann. Neurol.2009; 66:843-57.

ELOVL7 Antibody: Elongation of very long chain fatty acids protein 7, 3-keto acyl-CoA synthase ELOVL7, ELOVL FA elongase 7

ELISA, WB, IHC-P, IF

157388949

Liquid