Elsubrutinib
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
1643570-24-4
ABBV-105
BTK
Protein Tyrosine Kinase
C17H19N3O2
Elsubrutinib (ABBV-105) is a covalent, irreversible, potent, and highly selective inhibitor of Bruton’s Tyrosine Kinase (BTK), with an IC50 of 0.18 μM for BTK catalytic domain. It specifically inhibits BTK dependent cellular functions, including both BCR and FcγR mediated signaling. It also exhibits significant efficacy in pre-clinical mechanistic models of antibody production, as well as in models of rheumatoid arthritis and lupus.
Beschrijving
Elsubrutinib Beschikbaar in 100 mg. Bestel eenvoudig online met snelle levering.
Specificaties
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> 5x 10^5 Cells / Vial
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