EMAP-II Antilichaam

EMAP II is a cytokine that is specifically induced by apoptosis. The release of this cytokine renders the tumor associated vasculature sensitive to tumor necrosis factor. Its precursor is identical to the p43 subunit, which is associated with the multi tRNA synthetase complex. Therefore, proEMAP II may function in binding RNA as part of the tRNA synthetase complex in normal cells and in stimulating inflammatory responses after proteolytic cleavage in tumor cells. EMAP II inhibits angiogenesis of vascular beds and suppresses the growth of primary and secondary tumors without affecting normal tissues.

9255

Q12904

Q12904

Human

Produced from sera of goats pre-immunized with highly pure (>98%) recombinant hEMAP-II (human EMAP-II) .

Unconjugated

Primary Antibodies, Antibody Pairs

Signal Transduction, Chemokines & Cytokines

Anti-hEMAP-II specific antibody was purified by affinity chromatography employing immobilized hEMAP-II matrix.

Batch dependent

None

Room Temp

EMAP-II antibody is stable for at least 2 years from date of receipt at -20˚ C. The reconstituted antibody is stable for at least two weeks at 2-8˚ C. Frozen aliquots are stable for at least 6 months when stored at -20˚ C. Avoid repeated freeze-thaw cycles.

AIMP1

Aminoacyl tRNA synthetase complex-interacting multifunctional protein 1

Homo sapiens

P43, HLD3, EMAP2, SCYE1, EMAPII, Aminoacyl tRNA synthase complex-interacting multifunctional protein 1, Multisynthase complex auxiliary component p43, EMAP-2

ELISA, WB

85700432

Lyophilized