Embellin
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
Inhibits the lysine acetyl transferase PCAF in vitro and in vivo (in vitro IC50=7.2 μM) . Inhibits H3K9 acetylation in mouse liver tissue while leaving levels of H3K14, H4K8, H4K12 unchanged1. Also inhibits X-linked inhibitor of apoptosis (XIAP) (IC50 = 4.1 μM, competing with Smac peptide) . Binds to the BIR3 domain, preventing XIAP interaction with caspase-9 and Smac. Induces apoptosis and alters gene expression profiles in breast cancer cells3. Possesses anti-inflammatory and analgesic activity in vivo4. Cell-permeable.
Unconjugated
Dark orange solid
-20°C
Beschrijving
Embellin Beschikbaar in 10 mg. Bestel eenvoudig online met snelle levering.
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