EML4 ALK F1174L Recombinant humaan actief eiwit Kinase
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
EML4-ALK is a fusion-type protein tyrosine kinase produced through gene rearrangement. EML4-ALK can be used for the study of non-small cell lung carcinoma (NSCLC) and neuroblastoma (NB) . EML4-ALK has multiple mutants. EML4 ALK F1174L Recombinant Human Active Protein Kinase is a recombinant EML4 ALK F1174L protein that can be used to study EML4 ALK F1174L-related functions[1].
12352211
Anaplastic lymphoma kinase (ALK)
Protein Tyrosine Kinase/RTK
Cancer
[EML4ALKF1174LRecombinantHumanActiveProteinKinase]
[1]Guan J, et al. ALK F1174S mutation impairs ALK kinase activity in EML4-ALK variant 1 and sensitizes EML4-ALK variant 3 to crizotinib. Front Oncol. 2024 Jan 9;13:1281510.
Room temperature
http://file.medchemexpress.com/batch_PDF/HY-E70714/
Enzyme
No Development Reported
Beschrijving
EML4-ALK is a fusion-type protein tyrosine kinase produced through gene rearrangement. EML4-ALK can be used for the study of non-small cell lung carcinoma (NSCL
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