EN450
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
793719-01-4
NF-κB
NF-κB
C11H13ClN2O3S
EN450 is a cysteine-reactive covalent molecular glue degrader targeting NF-κB. It interacts with allosteric C111 in the E2 ubiquitin ligase UBE2D that induces the ternary complex formation between UBE2D and NFKB1. It exhibits anti-proliferative effects through a Cullin E3 ligase and proteasome-dependent mechanism.
Beschrijving
EN450 Beschikbaar in 25 mg. Bestel eenvoudig online met snelle levering.
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