ENDOG Antilichaam - Middengebied: FITC (ARP52054 P050-FITC)

Endonuclease G

FLJ27463

2021

Q14249

NP_004426

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Zebrafish

The immunogen is a synthetic peptide directed towards the middle region of human ENDOG

ENDOG cleaves DNA at double-stranded (DG) n. (DC) n and at single-stranded (DC) n tracts. In addition to deoxyribonuclease activities, ENDOG also has ribonuclease (RNase) and RNase H activities. ENDOG is capable of generating the RNA primers required by DNA polymerase gamma to initiate replication of mitochondrial DNA.The protein encoded by this gene is a nuclear encoded endonuclease that is localized in the mitochondrion. The encoded protein is widely distributed among animals and cleaves DNA at GC tracts. This protein is capable of generating the RNA primers required by DNA polymerase gamma to initiate replication of mitochondrial DNA.

UBC; BIRC2; DNAJA4; STUB1; HSPA4; AIFM1; FEN1

FITC: Fluorescein Isothiocyanate

Polyclonal Antibody

WB

Affinity Purified

0.5 mg/ml

Cow: 93%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rat: 100%; Zebrafish: 100%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

28kDa

Varecha, M., (2007) Apoptosis 12 (7), 1155-1171

Wet Ice

297

ENDOG

ENDOG

Rabbit

Endonuclease G, mitochondrial

NM_004435

YVMPNAPVDEAIPLERFLVPIESIERASGLLFVPNILARAGSLKAITAGS