Endostatine
Gecertificeerd

Endostatine

Catalog #: 100-334-L250
Maat: 250 µg

Kwaliteit

ISO Gecertificeerd

Levering

24-48 uur

Prijs -1%
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Gratis verzending vanaf €100

Technische Specificaties

Description

Endostatin is a naturally occurring 20 kDa polypeptide derived from the C-terminal portion of type XVIII collagen. It functions as an anti-angiogenic cytokine that is expressed in various organs with the highest levels in liver, lung and kidney. Endostatin inhibits angiogenesis by blocking the pro-angiogenic activities of VEGF and FGF-basic. Recombinant human Endostatin is a 20.2 kDa protein consisting 184 amino acid residues.

Synonyms

COL18A1; KS; KNO; KNO1

NCBI Gene ID

80781

UniProt

P39060

Accession Number

NP_085059

Accession Number mRNA

NM_030582

Chromosomal Location

21q22.3

Reactivity

Human

Cross Reactivity

Human

Sequence

MHSHRDFQPV LHLVALNSPL SGGMRGIRGA DFQCFQQARA VGLAGTFRAF LSSRLQDLYS IVRRADRAAV PIVNLKDELL FPSWEALFSG SEGPLKPGAR IFSFDGKDVL RHPTWPQKSV WHGSDPNGRR LTESYCETWR TEAPSATGQA SSLLGGRLLG QSAASCHHAY IVLCIENSFM TASK

Endotoxin

< 0.1 ng/µg of protein (< 1EU/µg)

Purity

98% by SDS-PAGE & HPLC analyses

Bioactivity

Measured by its ability to inhibit HUVEC migration.

Length

184

Form

Lyophilized

Molecular Weight

20.2 kDa

Host or Source

E. coli

Beschrijving

Endostatin is a naturally occurring 20 kDa polypeptide derived from the C-terminal portion of type XVIII collagen. It functions as an anti-angiogenic cytokine t

Specificaties

ProductnaamEndostatine
Categorie
Beschikbare grootte250 µg
Catalogusnummer100-334-L250