
Endostatine
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
Endostatin is a naturally occurring 20 kDa polypeptide derived from the C-terminal portion of type XVIII collagen. It functions as an anti-angiogenic cytokine that is expressed in various organs with the highest levels in liver, lung and kidney. Endostatin inhibits angiogenesis by blocking the pro-angiogenic activities of VEGF and FGF-basic. Recombinant human Endostatin is a 20.2 kDa protein consisting 184 amino acid residues.
COL18A1; KS; KNO; KNO1
80781
P39060
NP_085059
NM_030582
21q22.3
Human
Human
MHSHRDFQPV LHLVALNSPL SGGMRGIRGA DFQCFQQARA VGLAGTFRAF LSSRLQDLYS IVRRADRAAV PIVNLKDELL FPSWEALFSG SEGPLKPGAR IFSFDGKDVL RHPTWPQKSV WHGSDPNGRR LTESYCETWR TEAPSATGQA SSLLGGRLLG QSAASCHHAY IVLCIENSFM TASK
< 0.1 ng/µg of protein (< 1EU/µg)
98% by SDS-PAGE & HPLC analyses
Measured by its ability to inhibit HUVEC migration.
184
Lyophilized
20.2 kDa
E. coli
Beschrijving
Endostatin is a naturally occurring 20 kDa polypeptide derived from the C-terminal portion of type XVIII collagen. It functions as an anti-angiogenic cytokine t
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