Endotheline 1 Adenovirus (Ad-ET-1)
Gecertificeerd

Endotheline 1 Adenovirus (Ad-ET-1)

Catalog #: 1373
Maat: 200 µL
Droogijs Vereist

Kwaliteit

ISO Gecertificeerd

Levering

24-48 uur

Prijs -1%
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Gratis verzending vanaf €100

Technische Specificaties

Description

The endothelins are family of cysteine-rich peptides consisting of 21-amino acid and containing two intramolecular disulfide bridges that exert their vasoactive and mitogenic actions through G protein-coupled receptors. At the present, the existence of three active isoforms of ET (-1, -2, and -3), and two distinct receptors, ETA and ETB, is well documented (17) . The active form of ET-1 arises from biologically inactive big-ET-1 through the action of a specific protease that removes 18 amino acids from its carboxyl terminal. This membrane-bound metallopeptidase, characterized by its sensitivity to phosphoramidon, is known as endothelin-converting enzyme-1 (ECE-1) . A growing body of evidence indicate that ET-1 is a major player in numerous disease states including congestive heart failure, pulmonary fibrosis, obesity and diabetes, as well as a key mediator of tissue repair and normal wound healing.

Product Name Alternative

Endothelin 1 Adenovirus

UNSPSC

41106621

HS Code

3822190000

Type

Pre-Made

Shipping Conditions

Dry Ice

Storage Conditions

-80C

Shelf Life

12 Months

Short Name

Ad-ET-1

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

CMV (ubiquitous)

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Ttiter

1x10^10 PFU/ml

Beschrijving

The endothelins are family of cysteine-rich peptides consisting of 21-amino acid and containing two intramolecular disulfide bridges that exert their vasoactive

Specificaties

ProductnaamEndotheline 1 Adenovirus (Ad-ET-1)
Categorie
Beschikbare grootte200 µL
Catalogusnummer1373