ENG Antibody - N-terminal regio : HRP (ARP33068_T100-HRP)

Endoglin

END, HHT1, ORW1

2022

P17813

NP_000109

Human, Mouse, Rat, Guinea Pig

The immunogen is a synthetic peptide directed towards the N terminal region of human ENG

Endoglin is a homodimeric transmembrane glycoprotein highly expressed by endothelial cells. It is a component of the transforming growth factor beta receptor complex since it binds TGFB1 and TGFB3 with high affinity. Mutations in the endoglin gene produce hereditary hemorrhagic telangiectasia.

ENG; TGFBR2; TGFBR1; TGFB3; TGFB1; ACVRL1; TUFM; TCTEX1D4; TGFBR3; TGFB2; INHBA; BMP7; BMP2; ACVR2A; ACVR1; ACVR2B

HRP: Horseradish Peroxidase

Polyclonal Antibody

IHC, WB

0.5 mg/ml

Guinea Pig: 91%; Human: 100%; Mouse: 91%; Rat: 91%

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

68kDa

Sanz-Rodriguez, F., et al., (2004) J. Biol. Chem. 279 (31), 32858-32868

Wet Ice

625

ENG

ENG

Rabbit

Endoglin

NM_000118

ILEVHVLFLEFPTGPSQLELTLQASKQNGTWPREVLLVLSVNSSVFLHLQ